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Cancer Pain

Cancer Pain: Causes, Symptoms, and Treatment Options

Cancer pain is a complex type of pain that can result from the cancer itself—as it invades or compresses tissues—or as a side effect of cancer treatments such as surgery, chemotherapy, or radiation. It may be acute or chronic, localized or widespread, and often requires a multidisciplinary approach for effective relief.


Cancer pain is highly individual and can range from mild and intermittent to severe and constant, affecting both physical comfort and emotional well-being. The goal of treatment is to control pain while maximizing quality of life.


Common Causes of Cancer Pain


  • Tumor infiltration into bones, nerves, or organs

  • Bone metastases from cancers such as breast, prostate, or lung cancer

  • Post-surgical pain after tumor removal or biopsy

  • Chemotherapy-induced peripheral neuropathy

  • Radiation-induced tissue damage

  • Cancer-related inflammation or obstruction (e.g., bowel, bladder)

  • Spinal cord compression from tumor growth or metastasis


Types of Cancer Pain


  • Nociceptive pain – caused by tissue injury or inflammation

  • Neuropathic pain – caused by nerve damage or compression

  • Visceral pain – from internal organs (e.g., liver, pancreas, bowel)

  • Breakthrough pain – sudden, intense pain episodes that “break through” baseline pain control

  • Phantom pain – pain in a limb or organ that has been surgically removed


Conservative & Medical Treatment Options


Medications

  • Non-opioid analgesics (e.g., acetaminophen, NSAIDs)

  • Opioids (e.g., morphine, oxycodone, fentanyl) for moderate to severe pain

  • Adjuvant therapies:

    • Antidepressants (e.g., amitriptyline)

    • Anticonvulsants (e.g., gabapentin, pregabalin)

    • Corticosteroids for inflammation and nerve compression

  • Topical agents (e.g., lidocaine patches, capsaicin cream)

  • Palliative sedation in end-of-life settings, when appropriate

Supportive Care

  • Physical therapy and mobility support

  • Psychological support and counseling

  • Palliative care coordination for symptom management and quality of life


Interventional Pain Management Options


For patients with refractory, severe, or localized cancer pain, interventional procedures can provide targeted relief with fewer systemic side effects:

Nerve Blocks

  • Celiac Plexus Block – for upper abdominal cancers (pancreas, stomach, liver)

  • Hypogastric Plexus Block – for pelvic and genitourinary cancers

  • Stellate Ganglion Block – for head, neck, and upper extremity pain

  • Peripheral nerve blocks – for localized tumor-related pain (e.g., chest wall, limbs)

Epidural or Intrathecal Pain Pumps

  • Deliver pain medication directly to the spinal fluid

  • Ideal for patients with widespread pain or intolerable medication side effects

  • Reduces need for high-dose oral opioids

Spinal Cord Stimulation (SCS)

  • May be considered for neuropathic cancer pain in selected cases

Radiofrequency Ablation (RFA)

  • Used to interrupt nerve pathways transmitting pain from cancer-affected tissues

Vertebral Augmentation (e.g., Kyphoplasty)

  • Minimally invasive procedure to treat painful vertebral compression fractures due to bone metastases


When to Seek Help


You should consult a cancer pain specialist if:

  • Your current medications aren’t relieving your pain

  • You’re experiencing significant side effects from pain medications

  • You have localized pain that may benefit from nerve-targeted treatments

  • Pain is affecting your ability to sleep, eat, or engage in daily life


Compassionate Cancer Pain Management


At Parkview Spine & Pain, we provide compassionate, comprehensive care for patients living with cancer. Our team works closely with your oncologists, surgeons, and palliative care team to create a personalized pain management plan, using the latest in interventional and supportive treatments to improve comfort and preserve dignity.


👉 Schedule your consultation today to explore safe, effective options for cancer-related pain relief.

Have a question about Cancer Pain?

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