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Trigeminal Neuralgia

Trigeminal Neuralgia: Causes, Symptoms, and Treatment Options

What Is Trigeminal Neuralgia?


Trigeminal neuralgia (TN) is a chronic pain condition that affects the trigeminal nerve, which is responsible for facial sensation. It causes sudden, severe, electric shock-like pain typically on one side of the face—most often affecting the cheek, jaw, or around the eye.

Even mild stimulation like brushing teeth, eating, or a light breeze can trigger episodes of excruciating pain. Trigeminal neuralgia can significantly disrupt daily life but is treatable with a range of options.


Common Causes


Trigeminal neuralgia occurs when the trigeminal nerve is compressed or irritated, often by a nearby blood vessel (neurovascular compression). Other causes include:

  • Multiple sclerosis (MS) – Demyelination of the trigeminal nerve root

  • Tumors or cysts pressing on the nerve

  • Post-herpetic neuralgia following shingles

  • Facial trauma or dental procedures

  • Idiopathic cases (no identifiable cause)


Symptoms


  • Sudden, stabbing, or shock-like pain on one side of the face

  • Pain triggered by routine activities like talking, chewing, or washing the face

  • Episodes lasting from seconds to minutes, often recurring in clusters

  • Tingling or numbness may be present in some cases

  • Can progressively worsen without treatment


Non-Surgical Treatment Options


Medications

  • Anticonvulsants (e.g., carbamazepine, oxcarbazepine) – First-line therapy

  • Baclofen – Muscle relaxant that can be used adjunctively

  • Tricyclic antidepressants – For patients with mixed pain profiles

  • These medications can reduce nerve excitability and suppress painful episodes.

Lifestyle Modifications

  • Identifying and avoiding known triggers (e.g., cold wind, brushing teeth)

  • Stress management techniques to reduce flare-ups


Interventional Treatment Options


When medications become less effective or cause intolerable side effects, interventional options can provide targeted, longer-lasting relief:


Trigeminal Nerve Blocks

  • Injection of a local anesthetic and steroid near the trigeminal nerve branches

  • Used for diagnostic and short-term relief of acute flares

Sphenopalatine Ganglion Block (SPG)

  • Minimally invasive procedure using a small catheter inserted into the nasal passage

  • Can reduce facial pain by modulating autonomic nerve signals

Radiofrequency Ablation (RFA)

  • Heat-based ablation of targeted nerve fibers to interrupt pain transmission

  • Provides longer-term relief, especially for patients with frequent attacks

Glycerol Rhizotomy or Balloon Compression

  • Performed under imaging guidance to selectively damage pain-conducting fibers of the trigeminal nerve

  • Often done by a neurosurgeon in recurrent or medication-resistant cases

Peripheral Nerve Stimulation (PNS)

  • Implantation of a small device to stimulate specific nerve branches

  • A newer option for patients with chronic, refractory facial pain


When Is Surgery Needed?


If interventional and medical therapies fail, neurosurgical procedures may be considered:

  • Microvascular Decompression (MVD) - A surgical procedure that relocates or removes the blood vessel compressing the trigeminal nerve. Often preferred for long-term control in younger, healthy patients.

  • Gamma Knife Radiosurgery - A non-invasive technique using focused radiation to damage the nerve root and reduce pain over time.


Conclusion

Trigeminal neuralgia is a uniquely painful condition, but patients today have access to a wide range of effective treatments—from medications to advanced interventional pain procedures and minimally invasive surgical options. Early diagnosis and a personalized treatment plan are essential for achieving meaningful and lasting relief.


👉 Schedule a consultation with our specialists to explore your best path toward relief.

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